语文S版五年级下册《孔子》语文教案(5)
2019-12-14 01:02
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inrats.thepharmacokineticparametersofecb一glueuronidewereestimatedinratsfollowingasingle一doseoraladministrationof100mg/kg.inrats，ecbwasrapidlymetabolizedtoitsmonoglueuronideandtheglueuronidewastheonlydrug一derivedeompoundelearlydeteetedinplasma.two一eompartmentmodelwasusedtoestimateecb一glueuronidepharlllaeokineticsbyusingdassoftware.theplasmaprofileofecb一glueuronidewasfoundtoberapidwithanapparenttmaxoeeurringat4h，indieatingthatecbwasrapidlyabsorbedinratsfollowinganoraladministration.inratsfollowinganoraladministrationofnca，nometaboliteswereevidentlydetectedinplasma.moreover，theparentdrugncawasobservedinplasmaonlyintraceamounts，indieatingthattheoralabsorptionofncainvivomaybepoor.onereasonleadingtothepoororalabsorptionofncawasprobablytheinvolvementofp一gp.v11浙江大学博士学位论文英文摘要4.metabolismofecbandncastudiedinvitrowithhumanlivermierosomes，hepgzcellsandreeombinanthumanenzylllesthemetabolieprofileinhumanlivermicrosomeswaseonsistentwiththatobservedinratlivermierosomesandrats，indieatingglueuronidationwasprobablythemajormetaboliepathwayofecbinhumans.wllenncawasineubatedwithhumanlivermicrosomes，onlyonemonoglucuronidewasobserved.theeatalytieisoen-zylllesprobablyinvolvedinecbandncametabolisminhumanswereidentifiedbyusingseleetiveehemiealinhibitioninhumanlivermierosomesandreeoxnbinanthumanenlzyllles.theresultsindieatedcyp3a4，ugtia6/9，espeeiallycyp3a4andugtia6，wereimportanteatalytieen-zylnesinecbmetabolism.ugtia3/6/9wereimportantcatalyticenzymesinncaglucuronidationmetabolism.nometabolitesweredeteetedafterncawasineubatedwithhepgzcells:noglucuronideandonlytraeemonoh州roxylationmetabolitewereobservedafterecbwasineubatedwithhepgzeells，indicatingthemetabolicabilitytowardecbandnca15verylow.keywords:ebraeteolataeompoundb:neochamaejasmina:recombinanthumanenzyllles
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语文S版五年级上册《孔子》语文教案 教学目标： 1、引导学生理解课文内容，了解孔子在中华文化史上的重要地信和他的一些思想郑 2、僻生联系上下文理解重点句子，指导学生默读课文。
而不是再揣测他派了条老船